Lithium

links: reference: 10-28-2021

Lithium #

• Lithium citrate for Canavan disease
  • Dcreases levels of N-Acetylaspartate in Canavan disease, increases levels in Bipolar (where NAA levels are abnormally low) and does not appear to affect levels in normal subjects.
  • https://raypeatforum.com/community/threads/brain-metabolism-predicts-fluid-intelligence-and-creativity.10241/post-144234
• Insulin signaling as a therapeutic mechanism of lithium in bipolar disorder
• Low dose lithium supplementation activates Wnt/β-catenin signalling and increases bone OPG/RANKL ratio in mice
• Lithium application to dermal fibroblasts blocks the interaction between GSK-3β and p53, causing cells to enter a (reversible) quiescent state.