KW-6356

2024-09-09:

KW-6356 #

• A2A inverse agonist.
• In vitro pharmacological profile of KW-6356, a novel adenosine A2A receptor antagonist/inverse agonist
• Has the pharmacologically active metabolite “M6”. Also an A2A antagonist/invers agonist. Its half-life might be anywhere between 4.34 hours and something like 18-24 lol.
  • In in vitro metabolism studies of KW-6356, 11 metabolites including an oxidation product (M2), an oxidation and reduction product (M3), a hydrolysis product (M4), and a monohydroxy product (M6) were observed in human hepatocytes.