yana-notes

Estradiol

links: Estrogen Hormones Steroid Neurosteroid reference: http://raypeat.com/articles/articles/estrogen-age-stress.shtml 4-11-2021

Estradiol #

Estradiol: 21.8-30.11 pg/mL is a good, low range.

  • Most common type of estrogen, followed by estriol and estrone. (4/12 I got 30.9) Concentration in tissues can be 50x higher than in plasma.

  • Decreases DAO activity R

  • Sensitizes mGluR5, which makes Cocaine much more euphoric for women. R

  • Stimulates Cortisol production

    • http://raypeat.com/articles/articles/estrogen-age-stress.shtml
      • Adrenal glands from a patient with ACTH-independent Cushing’s syndrome, whose symptoms worsened during pregnancy and oral contraceptive use, were cultured in different concentrations of estradiol. Estradiol stimulated cortisol secretion in a dose-response manner in the absence of ACTH." . “This is the first description of estradiol stimulation of cortisol production by cultured adrenal cells in ACTH-independent Cushing’s syndrome.”

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