Phenylpiracetam
links: Racetams reference: https://www.reddit.com/r/Nootropics/comments/jzw1zd/phenylpiracetam_a_review_of_russian_scientific/ 4-13-2021
Phenylpiracetam
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Affects the Casein Kinase enzymes. It could possibly exacerbate milk allergies due to this - very interesting.
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Agonizes α4β2 nAChR with IC50=5.86μm. Binds to the recognition site.
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- 100mg/kg (HED>1g: madness)
- I’ll have to look and see if all the effects measured were all after taking scopolamine.
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Possible actions on DAT: S-phenylpiracetam, a selective DAT inhibitor, reduces body weight gain without influencing locomotor activity .
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https://www.freepatentsonline.com/EP2891491A1.pdf (Ratz) (10mg/kg HED = ~113mg)
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- I’m not pro enough at Neural Oscillations to understand what everything being lower implies. Like what are they oscillating at then?
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It’s not metabolized, it is merely excreted - 40% kidneys and 60% bile/sweat.
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Neuroprotective and anti-inflammatory activity of DAT inhibitor R-phenylpiracetam in experimental models of inflammation in male mice its enantiomer.
Methylphenylpiracetam #
- Pretty much just a σ1 PAM.
Phenypiracetam hydrazide (RGPU-95) #
5-10x potency.
Supplementation #
- Dose: x1-3 100-300mg. ~100% bioavailability.
- If you felt like taking a 500mg-1g though, it would generally be more powerful than amphetamine.
- Timing: 20-60 onset, 1~ hour peak, 3-5 hour half-life
- Tolerance takes ~1-2 weeks to return to baseline. And it may have cross-tolerance with other racetams at that.
- But guess what? Russian research protocol thing: 100mg daily one month on, one month off. After a few days, subtle cognitive effects will build up.
- Fat-soluble.
- Much more stimulating than the rest. Improves athleticism. Analytic/mathematical, repetitive tasks, robotic. Less empathy, anxiety killing, irritable, horny. low inhibition, talkative