Lactate
links: reference: https://en.wikipedia.org/wiki/Lactic_acid#Exercise_and_lactate https://www.livestrong.com/article/470283-what-is-the-difference-between-lactic-acid-lactate/ 6-4-2021
Lactate
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During Exercise, glucose is broken down and oxidized into pyruvate, and lactate is produced from the pyruvate faster than the body can process it.
- The production of lactate is beneficial for the regeneration of NAD+, which is used up in oxidation of the intermediate Glyceraldehyde 3-Phosphate during the production of pyruvate from glucose.
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During intense exercise, NAD+ cannot regenerate quickly enough. The resulting lactate is either:
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Oxidated back into pyruvate, to be used in the Citric Acid Cycle, or converted to glucose via Gluconeogenesis/Cori cycle.
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Muscle under intense work becomes acidic. Lactate counteracts depolarization of cells, which is “the burn”. It seems to be your friend, but the Peat fan club is not a fan; it activates many mediators of inflammation.
- Lehninger, A. Bioenergetics: The Molecular Basis of Biological Energy Transformations. 1973
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To maintain cellular energy, it must be removed through the kidneys, or in the absence of electrolytes/kidney function, the skin.