Copper
links: Vitamins & Minerals reference: https://www.aetherometry.com/publications/direct/JAethRes/JAR02-03-01.pdf 4-11-2021
Copper #
- Excess copper converts Dopamine to noradrenaline? I suppose Cu helps with catecholamine synthesis?
Supplementation #
Relatively stable in the body; it only needs to be supplemented every few days, unlike zinc.
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Copper and Iron compete for absorption
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Zinc inhibits copper absorption. A higher copper to zinc ratio increases oxidative stress, inflammation, diabetes, and sleep disturbances. Ratio of copper to zinc should be 1:5 or maybe 1:8.
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Excessive intake of vitamin B6, vitamin B3, vitamin B5, vitamin A, or vitamin C can exacerbate a copper deficiency R
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- Cuproptosis is a novel form of regulated cell death reported this year, and no study has reported the relationship between ASD and cuproptosis.
- 4 genes:
- FDX1 (ferredoxin: Cu2+ reducer) promotes lipoylation and abberant oligomerization of DLAT (dihydrolipoyl transacetylase, part of the PDH complex).
- Lipoic Acid synthase decreases cell sensitivity to cuproptosis by blocking the lipoylation of proteins (even though it’s synthase?)
- ATP7B were crucial genes in the cuproptosis signaling pathway for ASD.
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Requirements for copper increase with increased Carbohydrate intake.
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MitoSynergy