Carbohydrate

links: reference: 4-11-2021

Carbohydrates #

• https://raypeatforum.com/community/threads/how-the-sugar-industry-shifted-blame-to-fat.15368/page-2#post-209906 - Essentially, saturated fat needs to be low for “carbosis” to occur.
  • PUFA Beta-oxidation does not interrupt interrupt ongoing carbohydrate metabolism a-la Randle Cycle, while Saturated Fat does.
    • Randle Cycle is applicable to all tissue except the liver, brain, and heart.
      • The Randle cycle revisited: a new head for an old hat
        • Stress Overrides Fatty Acid Inhibition of Glucose Metabolism
  • Insulin Resistance is required for a ketogenic diet.
  • https://high-fat-nutrition.blogspot.com/2015/10/protons-and-ultra-low-fat-once-more.html
    • Dude derives the Electron Transport Chain from the ground up and optimizes it. It evades me as it is so hold on.
    • Cellular insulin resistance is controlled by Superoxide produced at Complex I, which exits the mitochondria as Hydrogen Peroxide:
    • Saturated fat causing mitochondrial insulin resistance via decreased ΔΨ
      • The more unsaturated the fatty acid, the lower the FADH 12:NADH ratio, supporting Electron Transport Chain Complex I forward flow; they keep ΔΨ High (how..?), and allow insulin to continue to function.
• [Second-meal effect: low-glycemic-index foods eaten at dinner improve subsequent breakfast glycemic response]
  • The glycemic responses to breakfast were significantly lower on mornings after low-GI dinners than after high-GI dinners.

Chemistry #