TNF

2022-02-19 links: reference:

TNF (Tumor Necrosis Factor) superfamily #

Family of transmembrane proteins. Function as Cytokines. There are 19 of them.

1. TNF-β
2. TNF-α
3. TNF-γ
4. Ectodysplasin-A

• Receptors: There is 1-19, 21, 25, 27.
  1. TNFR1
  2. TNFR2
     • Higher levels of soluble TNFR2 in Schizophrenia. Increases tumor growth; increased expression seen in Cancer.
  3. LNGFR (p75)
  4. Ectodysplasin-A receptor.