Selenium

links: Vitamins & Minerals reference: https://raypeatforum.com/community/threads/peats-surprising-response-to-my-email-a-ray-peat-vegan-is-possible.8939/

• Selenium supplementation inhibits IGF-1 signaling and confers methionine restriction-like healthspan benefits to mice 8-12-2021

Selenium #

In food exists as various selenoamino acids such as Selenocysteine. This is not detected by flame spectroscopy for nutrition fact labels.

• Selenium deficiency aggravates the effects of Vitamin E deficiency

• Along with vitamin E, induces apoptosis.

• Adequate levels are necessary for thyroid hormone metabolism.

• Required for the enzyme that deiodinizes T4 to convert into T3.

• Probably pretty underrated. Counteracts the toxicity of heavy metals. Seafood allergy = iodine allergy = selenium deficiency. Without it, iodine is inflammatory.

• An imbalanced selenium to copper ratio can contribute to oxidative stress R Peat: “Selenium is one of the extremely protective nutrients that prevent atherosclerosis in animal experiments with excess cholesterol.”

• Selenium mediates exercise-induced adult neurogenesis and reverses learning deficits induced by hippocampal injury and aging

• Selenium Supplementation Affects Insulin Resistance and Serum hs-CRP in Patients with Type 2 Diabetes and Coronary Heart Disease

  • Reduction in C-Reactive Protein and serum insulin.

• Selenium supplementation inhibits IGF-1 signaling and confers methionine restriction-like healthspan benefits to mice (sodium selenite)

  • The promotion of lifespan by Methionine restriction is possibly simply by means of inhibiting IGF-1.

• Dietary selenium intake modulates thyroid hormone and energy metabolism in men

  • 47μg/d for 3 weeks, then either 14 or 297 for 99 days. T3 increased in the former group, decreased in the latter (along with increase in TSH)

Supplementation #

• RDI = 55μg.
• Anti-thyroid at about 120 μg.
• Selenoexcell (selenized yeast),
• Sodium selenite is pro-oxidant. I think amino acid forms are best like L-selenomethionine (~97% absorption).
• exists in food as selenocysteine or maybe selenide.
• There’s also methylselenocysteine.
• 1 brazil nut has 1g of ω-6 and 90 μg of selenium. But this selenium content of course varies depending on where they’re grown.
• Cherimoyas have heaps
• Selenium = 250x100 μg=$10 is the best deal out there for L-Selenomethionine at least.