IGF-2

2022-05-29: reference:

IGF-2 #

It’s magic. Completely reverses age-related cognitive decline past control in transgene administration.

• In APP models of alzheimers, IGF2 transgene administration completely reversed cognitive dysfunction in these mice and then their cognition and dendritic outgrowth was 50% longer than control mice and had stronger cognitive functions than young wildtype mice.
• Strong mechanistic data supporting IGF-2 gene repeats and IQ, and MGF overexpresson and significantly slowed neural stem cell niche decline.
• Tumors, IGF-2 and Hypoglycemia: Insights from the clinic, the laboratory and the historical archive
  • Elevated IGF-2 levels are associated with suppressed plasma levels ofInsulin, IGF-1, Growth Hormone
• Association of the insulin-like growth factor II (IGF2) gene with human cognitive functions correlated with extremely high Intelligence.
• Insulin-Like Growth Factor II Targets the mTOR Pathway to Reverse Autism-Like Phenotypes in Mice
• Insulin-like Growth Factor 2 Rescues Aging-Related Memory Loss in Rats