Glycine
links: reference: Amino Acid 4-16-2021
Glycine
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Its R group is technically just a single hydrogen:
An important non-essential amino acid.
- Inhibits Histidine. Contraindicated with hypercalcemia.
- Can slow down peristaltic movement and cause constipation.
- Inhibits Orexin.
- One thing I want to know is how you can expect it to be excitatory or inhibitory, considering it’s an agonist both of NMDARs and GABA receptors.
- Increases 5-AR in the brain apparently
- A buffer of Methyl Groups; it gets methylated when there’s excess, and doesn’t get methylated when there is too little.
- Very helpful for maintaining stable Blood Glucose.
- Protects against abosbred endotoxins. So it’d be nice during a meal.
- For some reason Landshark said it helps with acid reflux for whatever reason. So I think it’d be good to add to sweet Potatoes. Olive continues to be 1 step ahead of me. It has a not unpleasant sweet flavor so you don’t notice it all. Maybe I’ll have a few grams with it especially if I want to add the 10+ to get Mike’s recommendations (and Olive ALSO did 5g 3x/day, along with 5g of taurine 3x/day.)
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Sustained saturating level of glycine induces changes in NR2B-containing-NMDA receptor localization in the CA1 region of the hippocampus
- Mice lacking 50% of the glycine transporters express more extracellular NR2B
Supplementation #
- Mike Fave recommends .2g/kg of body weight daily! So like a good 15.
- Most do like a few grams before bed.