3β-HSD
links: Enzyme reference: 5-2-2021
3β-HSD (3β-Hydroxysteroid Dehydrogenase) #
Important enzyme in Steroidogenesis. The only enzyme in the adrenal pathway of corticosteroid synthesis that is not a member of the Cytochrome P450 family. Converts:
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Pregnenolone into Progesterone
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DHEA into Androstenedione
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5α-DHP into 3beta,5beta-tetrahydroprogesterone.
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Potently inhibited by various drugs which work as steroidogenesis inhibitors.