Steroidogenesis
links: Steroid reference: 4-11-2021
Steroidogenesis #
The story goes like this: The Hypothalamus secretes Gonadotropin-releasing Hormone to stimulate the Pituitary Gland, which secretes Luteinizing Hormone and FSH. The fun begins when LH stimulates leydig cells to use StAR to begin steroidogenesis.
- Gene names for my reading convenience:
- 17α-Hydroxylase = CYP17A1
- 21-Hydroxylase = CYP21A2
- Aldosterone Synthase = CYP11B2
- Aromatase = CYP19A1
(Red arrows are the androgen backdoor pathay)
(This differs slightly from the chart above and I don’t know who to trust anymore).
- Not shown is the α and β differences for some of these; I’m not sure where they begin or end.