yana-notes

11β-HSD

links: Steroidogenesis reference: 4-21-2021

11β-HSD #

Type 1 converts Cortisone into Cortisol, while type 2 does the reverse.

  • Vitamin D and Vitamin A reduce 11β-HSD. Just 2,000 IU per day decreased cortisol by 40%: R
  • Part of drug metabolism, like Bupropion -> Threo-hydrobupropion.