yana-notes

Ventral Tegmental Area

links: Neuroanatomy Neural Circuit reference: The wiki page is pretty rich 11-3-2021

Ventral Tegmental Area (VTA) #

  • Subvided into the nucleus paranigralis, nucleus parabrachialis pigmentosus, nucleus interfascicularis, and the nucleus linearis caudalis and rostralis.
  • A ‘group of neurons’. The origin of dopaminergic neurons of the Mesolimbic Pathway-Mesocortical Pathway; ~60% Dopaminergic projections, and then GABAergic Interneurons/projection neurons.
    • It projects to:
      • Amygdala
      • Entorhinal cortex
      • Cingulate gyrus
      • Hippocampus
      • Nucleus accumbens
      • Olfactory bulb
      • Prefrontal cortex
  • The tail of the ventral tegmental area (tVTA)
  • Receives Glutamatergic input from the prefrontal cortex, and inputs from other areas like NAcc, pallidum, etc. Most of the proections are to the ventromedial striatum. R
  • Receives GABAergic input from:
    • Nucleus accumbens
    • ventral pallidum
    • Dorsal raphe nucleus
    • Lateral hypotahalmus
    • Periaqueductal gray