Sterculic Acid

2023-11-05:

Sterculic Acid #

• A cyclopropene fatty acid.
• According to wikipedia, These acids are highly reactive but the cyclopropene ring is destroyed during refining and hydrogenation of the oils. In the study below, they put it in the PUFA section even though it looks MUFA to me, but maybe it’s just as reactive? Brad from fireinabottle did mention it could maybe cause inflammation
• Inhibits SCD and PPAR-γ. Thus, especially when you combine it with PPAR-α stimulators (berberine, etc.) à la the fire in a bottle protocol, it facilitates replacement of PUFA/MUFA in the body with SFA.
• https://fireinabottle.net/sterculia-oil-prevents-liver-fat-accumulation-and-prevents-insulin-resistance-in-fructose-fed-rats/
  • Buy dat shit: https://fire-in-a-bottle.myshopify.com/products/sterculia-oil-pre-order-4-oz-ships-in-january
    • But in any case he only recommends like, 1.2g of it (2 squeezes)
  • https://fireinabottle.net/accumulating-linoleic-acid-prevents-diabetes/the DI1600/DI1800 = desaturation index for 16/18-carbon FAs, which is basically a proxy of SCD activity. Get a blood test for palmitoleic acid and palmitic acid, divide them, multiply by 100.a
  • Some measures in the fructuse+sterculic group is even lower than control:
  • Preventive Action of Sterculic Oil on Metabolic Syndrome Development on a Fructose-Induced Rat Model
    • In the standard diet + sterulic group, it increased both stearic and oleic acid content of adipose to about an equal extent… also slightly increased body weight gain. I’m not sure if it was totally equicaloric though. But most importantly, even in the fructose+SO group it lowered both DI16 and DI18.

• People aren’t seeing any results on reddit. Mixed opinions about the taste.