Δ9 Desaturase
2022-08-17: reference:
Δ9 Desaturase (Stearoyl-CoA desaturase-1/9-desaturase) #
(FADS2 also has Δ8 and Δ4 activity apparently)
Rate-limiting step of Monounsaturated Fat synthesis:
I’ve seen it described as an AKT activator/AMPK inhibitor.
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Insights into Stearoyl-CoA Desaturase-1 Regulation of Systemic Metabolism
- In SCD1 GKO mice, reduced hepatic oleate synthesis reduces liver triglycerides accumulation
- Inhibits FAAH
- Lower the better.
