yana-notes

PPAR-γ

2022-05-18: reference:

PPAR-γ #

  • ‘Master regulator of adipogenesis’; Knockout mice have zero Adipose tissue.
    • (tyw says it is supposed to upregulate carbohydrate metabolism)
  • Though some studies talk about lipolysis, its net action is promoting lipogenesis.
  • Promotes proliferation (as opposed to differentiation into adipocytes) of proadipocytes.
  • Promotes M2 Macrophage phenotype.