Neuropeptide Y
2022-06-25: reference:
Neuropeptide Y #
- Actually the most abundant peptide in mammalian CNS.
- Increases food intake and fat storage, anxiolytic, analgesic, vasoconstrictor.
- Acts upon Neuropeptide Y GPCRs, of which there are at least 5.
- I believe serotonin lowers it - this is how the effects of antagonists like Cyproheptadine come to fruition.
- Activated by some S6K-mediated pathway in the hypothalamus
- Stimulates the rostral migratory stream.