Hypothyroidism

links: reference: 4-20-2021

Hypothyroidism #

• We went from diagnosing 30-40% of Americans as hypothyroid in the ‘40s to only 1-5% now because of an inaccurate test. We also went from prescribing T3:T4 in a 1:4 ratio to prescribing isolated synthetic T4. https://twitter.com/Rizzenhouse/status/1749868568374804790

• Hypothyroidism is a slowed conduction along nerves; slow recovery+readiness for new response. This leads to slow reaction time and its related mental deifcits (slowed memory, perception, etc.)

• Plasma noradrenaline and blood pressure in hypothyroid patients: effect of gradual thyroxine treatment

  • Higher plasma Norepinephrine levels.

• Symptoms include:

  • Chronic fatigue
  • Weight gain
    • One can have a fast metabolism while hypothyroid - when calories are wasted by heat, rather than producting CO2/ATP.
  • Consitpation
  • Cold sensitivity
  • Depression
  • Reduced endurance
  • Ireggular/heavy menses
  • Accumulation of mucopolysaccharides - combinations of proteins and sugars deposited in extracellular space. These can accumulate in the scalp in those with MPB and act as a matrix for calcification.
  • Poor Glycogen storage

• While symptoms of hyperthyroidism include:

  • Muscle weakness
  • Tremors
  • Increased sweating
  • Heart palpitations
  • Weight loss
  • Sleep disturbances
  • Heat sensitivity

Hashimoto’s #

Excessive Estrogen can lead to Hashimoto’s (Thyroid nodules are more common in women and increases with advancing age) via increasing the anti-TOP antibodies, like autoantigen thyroid peroxidase. R Autoimmune disease resulting in gradual destruction of the thyroid gland; naturally resulting in Hypothyroidism. Grave’s disease leads to a hyperactivity of the thyroid gland.