GLUT4
links: reference: 8-25-2021
GLUT4 #
- The Insulin-regulated GLUT. Creatine and DHT boosts it.
- Liberated from vesicles via Protein Kinase C (via PI3K->PDK1/2)
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Exercise and insulin sensitivity: a review
- Up to two hours after exercise, glucose uptake is in part elevated due to insulin independent mechanisms, probably involving a contraction-induced increase in the amount of GLUT4 associated with the plasma membrane and T-tubules.
- A single bout of exercise can increase insulin sensitivity for at least 16 h post exercise in healthy as well as NIDDM subjects. Recent studies have accordingly shown that acute exercise also enhances insulin stimulated GLUT4 translocation
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Glucose, exercise and insulin: emerging concepts
- Other glucose transporter isoforms such as GLUT1 and 5 are expressed at much lower levels than GLUT4 in skeletal muscle.