DeFibron

links: reference: https://raypeatforum.com/community/threads/defibron-liquid-methylated-sfa-for-lab-r-d.17626/ 11-8-2021

DeFibron #

The aim here is to maximize the antifibrotic effects of saturated fats, which under normal circumstances are quickly metabolized into mitochondria into Acetyl-CoA. The ingredients herein aim to replicate, say, spoonfuls of coconut oil with hardly any caloric intake or digestion.

• This certainly prevents things, but does it heal? (#229, yeah it can attenuate measures of cardiotoxicity and stuff, but is it healing?)

30x50 drops, $40.

• Methyl stearate: 200mg

• Methyl myristate: 200mg

• Methyl palmitate, the star of the show: 800mg

  • Esterification via methyl group prevents activation from CoA.
  • Prevents inflammation and Fibrosis.
  • Increases Endotoxin resistance
  • Methyl palmitate reversed estradiol benzoate-induced endometrial hyperplasia in female rats
  • Effect of methyl 2-hexadecynoate on hepatic fatty acid metabolism
    • Caused a 25% decrease in body weight and the appearance of (((essential))) fatty acid deficiency symptoms within one weak. Dat PUFA depletion.
    • A shift from hgher molecular weight trigylcerides to lower. Long-chain 2-ynoic acids inhibit elongation of saturated and monoene fatty acids. I believe this means it rapidly depletes PUFA.
  • Depression of phagocytic activity and immune response by methyl palmitate
    • Depressed the Rough Endoplasmic Reticulum via interfering with tte phagocytic activity of Kupffer Cells.
  • Aortic/cerebral? Vasodilation - far more potently than nitric oxide.
  • Inhibits Fatty Acid Synthase
  • Lowers TGFβ.
  • Potent vasodilator!

• Can cause loose stools; probably increases Stomach Acid, leading to the gut/endotoxin benefits and increasing bowel transit. Caused somebody intestinal discomfort at first, but then it got great.

• Can make you smell weird, but P5P or magnesium is apparently great for that.

• Multiple people have reported a widening of vision, heightened sense of smell, and teeth sensitivity.

Supplementation #

• Powerful for some people at even 1 drop.
• 20 seems to be fine with me? People do 5 drops 3x/day and so on.
  • 5 drops, 3x day. Huge change in energy, mood, etc. I’ve literally never tried any change that improved my life as much as this tiny little thing right here. I believe that taking a small amount with every meal is the key. Its not so much a half life issue rather than nourishing the mucosa with each meal so that it gets stronger and stronger (instead of taking a step back when you have a meal w/o).