5-MeO-DMT

2024-11-23:

5-MeO-DMT #

• 5-HT1A affinity as opposed to 5-HT2A is where all the differences from DMT lie: 1000-fold greater affinity, whereas DMT is just 4-fold. LSD, psilocybin, mescaline are all very much ego killers. DMT? Completely different story. Lots of beings and forces in that realm are highly egoic. and 5-MeO is the opposite.
• Very potent at suppressing firing of Dorsal Raphe Nucleus neurons.
• https://heart.qri.org/retreats/2023-canada/andres-gomez-emilsson/key-insights
  • 5. Geometric frustration as the cause of dukkha and all the implications that this entails.
  • 6. The higher the dose, the higher the connectivity. Many effects might be modellable with ‘wormholes’ shortening the distance between parts of the experience.
  • 13. Drastically reduces titan realm construction
• https://heart.qri.org/retreats/2023-canada/andres-gomez-emilsson/levels
  • I do know several people who have taken it every day for several months and some of them say it was simply for spiritual development or exploration whereas others said it had an element of attachment to the feelings of euphoria
  • cf. Rob Burbea’s approach to insight practices, where he emphasizes the sense of relief and comfort they provide
    • https://qualiacomputing.com/2021/12/03/high-valence-meditation/
  • Flickering and Strobing as a tell-tell sign of Subconscious Clinging: During the state you can tell that you are clinging to something by how it makes the field strobe in somewhat unnatural ways. Let go and notice the cleaner resonances. This makes the insight that craving is always implemented with various contractions really clear.
• https://heart.qri.org/retreats/2023-canada/asher-arataki/5-meo-dmt-faq
  • 5-MeO narrows the metaphorical aperture of my nervous system while simultaneously expanding the overall scale of my conscious experience. At sufficiently high doses this results in experiences that seem to envelop the whole world and yet contain little to no information content, producing a state of profound non-separation.
    • 5-MeO expands the radius of your attention while simultaneously ‘dialling up’ the concentration of awareness within this expanded attentional region (also as a function of dosage). This process continues up until the point that your attention has expanded to envelop the entire field of your experience (around 8+mg), after which I found it impossible to ‘attend’ to any local regions
  • at higher doses I not only never saw colours but it is also inconceivable to me that there could exist colours. WTF?

Dose #

• Psychonautwiki:
  • Strong (likely breakthrough): 12-16-18mg
  • 18+ = whiteout
• https://heart.qri.org/retreats/2023-canada/andres-gomez-emilsson/levels:
  • 0.1-0.5 = sub-threshold. Subtle mindfulness; potentially useful for meditation.
  • 0.5-1 = threshold. Body load, slight anxiety, “A light transparent synesthetic film covers the field of experience”
  • 1-2.5 = oneness begins; the mind begins to degrade.
  • 2.-5mg = the last level where this is happening to “you” rather than the universe. A plasma-like state of consciousness develops, with absorption into stimuli. The self dissolves into a field-like energy body with eyes closed, and the felt sense of oneness, impermanence, and non-attachment are all really strong, yet there is the feeling of “a soul” to which all of this is happening.
    • Andres in the 12 key differences video says he doesn’t even advocate high doses. 5mg (2.5-7mg. He fully understands you can take either too much or too little) with meditation and a strong intention. You hear other people say this too, i.e. that low doses are much more rewarding, unlike N,N-DMT.
  • 5-7.5 = becoming the creative force of the universe.
  • 7.5-15 = Supernova.
  • 15+ = full dissolution of witnessing.

• As for pens: 2.4v-2.8. Any more than that and you run the risk of burning it.
• Acolyte = 25% concentration, or 250mg/mL.
  • The paper I got with this says a 5 second draw = 2mg. (Therefore, 2-5 long inhales (= 8-20 I suppose) for a breakthrough)