WAY-316606

2023-05-31:

Relatively novel substance on science.bio for Hair Loss. Comapre to SM04554 - both of them have human studies. This has been around for 3 years or so! Also KY19382, GT20029 - Haircafe has videos on all of them.
Generally, it might be the best out of the WNT drugs, since it doesn’t go intracellular and act on WNT directly, which may pose a cancer risk.

SFRP1 inhibitor, and SFRP is a WNT inhibitor.
- Another drug that does this is BIOSCALIN/Tricovel’s iSFRP , which comes in expensive scifi vials. $8 per vial which is used weekly
Haircafe video
- Has a few really cool references:
  - Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles
    - Yea, this is the MOA cyclosporine, which also has side effects/ is carcinogenic or something?

yana-notes