TLR4
2022-04-26: reference:
TLR4 (Toll-like receptor 4) #
- Endotoxin receptor, but also Fibrinogen, some opioids, Heat Shock Proteins, etc.
- Activates NF-κB (translocation from cytosol to nucleus, upregulating proinflammatory genes) and p38/JNK, STAT3.