yana-notes

Ras

2022-04-15: reference:

Ras GTPase #

Binds to GTP/GDP.

  • Superfamily consisting of:
    • Ras proper
    • as well as Rho, Rab, Arf, Ran, RGK, Miro. Rag? Let’s get this thing straight: it’s the RAS-RAF-MEK(1/2)-ERK(1/2) pathway. In some of these charts, that’s all there is to it in a linear fashion: 600
    • Downstream, you see Rho Rac, and Cdc42, which proceed into their own cascades.