Pyroglutamic Acid
1:40:20 Do you need to give up your job to practice the Dhamma? 2021-12-20 links: reference:
Pyroglutamic Acid #
- 
Derived from Glutathione via γ-glutamyl cyclotransferase. - As you’d expect, blood GSH decreases as PGA increases. R
 
- 
Converted to Glutamate via 5-oxoprolinase. - Only in high doses if supplemented.
 
- 
An oxidized form of Proline. 
- 
Sodium pyroglutamate is a humectant, and L-pyroglutamic acid is sold as a nootropic. 
- 
Pyroglutamic acid is a hydrating topical. 
- 
http://www.longecity.org/forum/topic/26237-neurotoxicity-of-pyroglutamic-acid/ - Supposedly is neurotoxic by promoting excitotoxicity and inhibiting brain energy metabolism via glutamate. Injected directly into rat brains. Purebulk - $13/100g