Phosphate
2022-01-22 links: reference: https://raypeat.com/articles/articles/phosphate-activation-aging.shtml
Phosphate #
- In inorganic chemistry I guess it’s a little different but in organic, phosphate basically = ‘Inorganic phosphate’ (Pi) refers to unbound phosphate anions, but I guess it’s referred to as organic when it forms an (AKA organo-)phosphate functional group, whether ionic or not.
- Vitamin D, Parathyroid Hormone, and α-Klotho are the 3 hormones responsible for its homeostasis in the body.
- Active transport of phosphate is regulated by calcitriol (1,25-dihydroxyVitamin D), which induces the expression of Npt2b on the apical membrane of intestinal epithelial cells. Low-phosphate diets also upregulate Npt2b expression independent of calcitriol, although the detailed mechanism of this regulation remains unclear."