PDZ

2022-04-27: reference:

PDZ domain #

The name is just an ‘initialism’ of the first ones to be discovered. Basically, they connect stuff.

• PDZ proteins include: ( There’s like 150 of ’em)
  • MAGUK (membrane-associated guanlyte kinases): PDZ, SH3, and GUK domains, et al.
    • “Discs large”
      • DLG1 (SAP-97)
      • DLG2 (PSD-93/chapsyn-110)
      • DLG3 (SAP-102)
      • DLG4 (PSD-95 or SAP-90)
      • DLG5
  • GRIP (glutamate receptor-interacting protein)
  • ABP (AMPA-binding protein)
  • PICK1 (Protein Kinase C interacting protein)
  • Homer simpson
  • SHANK (1, 2, 3)