yana-notes

Opioid Receptor

links: reference: 11-10-2021

Opioid Receptor #

  • Main subtypes:
    • μ-Opioid Receptor (1-3) (Gi)
    • κ-Opioid Receptor (1-3) (Gi)
    • δ-Opioid Receptor (1-2) (Gi)
    • Nociceptin Receptor (ORL)
      • Wikipedia calls this kappa type-3. But the kappa page does not acknowledge this.
    • Far less known is the ζ-opioid receptor which does much different things.
    • µ-receptors mediate many neuroendocrine functions, whereas δ-receptors prevail in peripheral tissue, particularly gastro-intestinal mucosa and intestine.