Nociceptin Receptor

2022-04-19: reference:

Nociceptin Receptor (OPRL1) #

AKA κ-Opioid Receptor 3? Gi-coupled. It’s similar in sequence to the opioid receptors, but it has little affinity for opioid peptides or morphine-like compounds.

• Activates K+ channels and inhibits Ca2+ channels.

• It can activate Phospholipase A2.

• Inhibits αCAMK II and Adenylyl Cyclase.