MAO-A
links: reference:
MAO-A #
- Degrades all amines, notably Serotonin and Tyramine.
- If you were MAO-A inhibited and you ate a lot of - especially aged - cheese, you’d get hypertensive crisis. Hope this isn’t the case for -B, homie!
- Serotonin -> 5-hydroxyindoleacetaldehyde
- Depression: 34% elevation of MAO-A in major depressive disorder
- Selective inhibition of MAO-A but not MAO-B activity increases rat pineal melatonin