Erythropoietin Receptor

2022-05-02: reference:

Erythropoietin Receptor #

Cytokine receptor. Promotes proliferation and rescue of Erythrocyte progenitors from apoptosis.

• EPOR normally forms a dimer like typical RTKs. EPOR (monomeric) Forms a heterotrimer with β common receptor.
• Erythropoietin: a candidate compound for neuroprotection in schizophrenia
  • Erythropoietin Receptors are densely expressed in the Hippocampus and cortex of those with Schizophrenia, but much less in control: especially the glia: wtf? Considering the title of the study it is presumed to be a defensive mechanism
  • Conditioned taste aversion: tests association of novel taste stimulus with illness. In schiophrenia this is impaired. This is mediated by the Medial Septum, which has very important hippocampal roles but also connects to the Nucleus Accumbens which is relevant here.