Central Pattern Generator

links: reference: 11-2-2021

Central Pattern Generator (CPG) #

A Neural Circuit (module) that produces rhythmic outputs, with a flexible response to input. Returns to its starting condition without fail after increasing/decreasing; oscillating.

Structure #

• They have an excitatory core/kernel of mutually excitatory interneurons provided by AMPARs and NMDARs.
• A ubiquitous component is pacemaker neurons, which repetitively depolarize independent of the network and in the absence of any synaptic input.
  • They require persistent sodium currents (NaP)