Biotin

links: Vitamins & Minerals reference: 8-18-2021

Biotin (B7) #

I believe it was discovered and extracted from a liver by Szent-Györgi.

• Underrated for preventing anaerobic Glycolysis.

• Avidin, a glycoprotein, is bound - possibly the tightest noncovalent bond seen in the body - to it, in raw Egg whites.

• Made by colonic bacteria, but does not supply adequate amounts.

• Excessive amounts can deplete B5, causing Acne.

• Astrocytes resolve ER stress through mitochondrial fusion facilitated by biotin availability

  • Induces Mfrn2 expression/localization under ER stress, augmenting its interaction with the mitochondria to exchange iomolecules.

Cofactor #

• Pyruvate Carboxylase

Supplementation #

• RDI = 30 μg, but it can be supplemented by the milligram for hair and such things.
• 1 cooked egg = 10 μg. 3oz beef = 4 μg. So not as easy a I thought! Youngsinatra takes 2.5-5mg a day or something. Most people for hair growth only take like sub-100μg. Purebulk has 1% powder (the rest being mannitol), thus basically 10mg = 100 μg.