Arrestin

2022-06-01: reference:

Arrestin #

• Es gibt Arrestin-1 (retinal stuff), arrestin-2 aka (β-arrestin), arrestin-3 aka (β-arrestin 2) and arrestin-4 (cone stuff). Participate in agonist-mediated desensitization of GPCRs, dampening signals.
• Activates JNK, AKT, Raf, Src, Bcl-2, PDZ-RhoGEF, β-catenin, and so on and so on.
  • β-arrestin → RAF → MEK → ERK1/2 → transcription.