c-Fos

8-16-2021 links: reference:

c-Fos #

• A proto-oncogene; an oncogene is a gene that has the potential to cause cancer. What the?

• Acute stress increases the amount of ACh released. “Our results suggest a model in which robust cholinergic stimulation triggers rapid induction of the gene encoding the transcription factor c-Fos” R

• SIRT1, and ΔFosB (with the help of ‘corepressors’ like JunD and by recruiting HDAC 1) downregulate its expression.