@Signaling in Striatal Neurons The Phosphoproteins of Reward, Addiction, and Dyskinesia (Girault 2012)

2022-04-20: reference:

@Signaling in Striatal Neurons The Phosphoproteins of Reward, Addiction, and Dyskinesia (Girault, 2012) #

DA neurons in the Substantia Nigra and the Ventral Tegmental Area are proposed to code for errors in reward prediction
- Fire in response to unexpected rewards, or to a conditioned stimulus that predicts the reward (Pavlov’s bell) but not the reward itself.
  - That last point is big, that dopamine is not released during the primary reward in conditioned learning. Or maybe it’s in another brain region
- Absence of expected reward inhibits firing