RSK2

2022-04-13: reference:

S6K2 (Ribosomal protein S6 kinase 2 (RSK2)) #

• Cross talk between ERK and PKA is required for Ca2+ stimulation of CREB-dependent transcription and ERK nuclear translocation
  • The sequential activation of ERK and RSK2 leads to the phosphorylation and transactivation of CREB… Ca2+-induced nuclear translocation of ERK and Rsk2 to the nucleus requires Protein Kinase A activation… the full expression of the late phase of long-term potentiation (L-LTP) and L-LTP-associated CRE-mediated transcription requires ERK activation.