Prepulse Inhibition

2021-11-19 links: reference:

Prepulse Inhibition (PPI) #

• A prestimulus (prepulse) inhibits an organism’s reaction to a stronger subsequent stimulus (pulse.) A lack of prepulse inhibition would be reflective of the information overload that those with Schizophrenia experience: “It has been sugested that the disrupting effect of the dopamine agonist apomorphine on PPI in rats might be based on reduced detectability of weak prepulse stimuli.”

Paired-pulse inhibition/suppression (PPI/PPS) is when (i’m gonna gsess) it’s a reduced response when multiple stimuli, probably one weaker, are presented simultaneously