Polyamine

2022-04-05: reference:

Polyamine #

Spermidine/sperime, and others. Not histamine though. Sperime is able to turn DNA into Z-DNA. Travis - I see polyamines as forming the link between cell biology and physical chemistry, unfurling the dNA of housekeeping genes…

Modulators of ion channels, i.e. Ionotropic Glutamate Receptors. Polyamines like Spermine block Kir Potassium Channels, decreasing outward currents.

• Besides having dedicated enzymes such as polyamine oxidase, excessive polyamines can also be degraded by the ubiquitous monoamine oxidase. The soy bean, despite having an unusaully high amount of polyamines, isn’t particularly correlated with colon cancer. So perhaps dietary polyamines—whatever their source—shouldn’t automatically be considered carcinogenic.