Parkinson's
2022-02-11 links: reference: https://www.fightingparkinsonsdrugfree.com/
Parkinson’s #
- Single-cell genomic profiling of human dopamine neurons identifies a population that selectively degenerates in Parkinson’s disease (May 2022)
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Serotonergic dysfunctions and abnormal iron metabolism: Relevant to mental fatigue of Parkinson disease
- 5-HT CSF level is significantly decreased, and levels of Iron and Transferrin are dramatically increased in the fatigue group.
- Low plasma serotonin linked to higher nigral iron in Parkinson’s disease
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https://raypeatforum.com/community/threads/serotonin-excess-not-dopamine-deficiency-may-be-the-cause-of-parkinson.29844/post-444771 The study makes the case that decreases in SERT proceed, and can measure the progression, of parkinsons. There is also a study linking it to dementia:
- https://raypeatforum.com/community/threads/higher-serotonin-availability-may-be-the-cause-of-cognitive-impairment-dementia.19349/
- Serotonin excess has also been shown to cause tremors, twitching, gait normalities, and such things. RPF