NLRP
2022-08-16: reference: https://raypeatforum.com/community/threads/nlrp3-inflammasome-cause-of-male-pattern-baldness.37563/ Hair Loss
NLRP (Nucleotide-binding oligomerization domain, Leucine rich Repeat) #
- NLRP: previously known as NACHT, LRR and PYD domains-containing protein 3. This is all one damn gene?!
- Asc = Apoptosis-associated speck-like protein containing a CARD (Caspase activation and recruitment domains)
- Pro-Caspase 1 is a ASC attached to p20+p10.
- NACHT = neuronal apoptosis inhibitor protein. LRR = leucine-rich repeat; PYD = Pyrin domain.
- Asc = Apoptosis-associated speck-like protein containing a CARD (Caspase activation and recruitment domains)
- It’s a bit complicated; some sources suggest different structures:
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