yana-notes

NAAG

2023-09-08:

NAAG #

  • Whereas the ability of NAAG to interact with NMDA receptors in a manner relevant to physiology is controversial, its primary receptor was long believed to be mGluR3.
  • Synthesized in neurons and glia. Synthesis is regulated by NAA availabilty.
  • PKA and PKC increase and decrease, respectively, quantity of NAAG in neuroblastoma cells.
  • Positive correlation between depression and thalamic NAAG.