KCNIP3

2022-05-20: reference:

KCNIP3 (Kv-channel interacting protein 3) #

• AKA Calsenilin or DREAM.
• DREAM (Downstream Regulatory Element Antagonist Modulator) contributes to synaptic depression and contextual fear memory
  • Overexpression impaired LTD but not LTP.
  • Interacts with PSD-95; probably the mechanism by which it decreases NMDAR EPSC intensity.
  • No difference in the subunits.
  • Ca2+-binding protein that binds to the DNA.