3α-Androstanediol

links: Steroid reference: 11-12-2021

3α-Androstanediol (5α-androstane-3α,17β-diol) #

• Binds to GABA-A as a positive allosteric modulator.

• Weak androgen and estrogen. Inhibitory androstane neurosteroid.

• High affinity for SHBG, similar to that of testosterone. Structural analog of DHT.

• Rewarding, anxiolytic, pro-sexual, anticonvulsant.