Tubulin
2022-09-16:
Tubulin #
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β-Tubulin has either GDP or GTP bound - the former is bound tighter.
- Hydrolysis is irreversible.
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Post-translational modifications of tubulin (2014)
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On the biophysical properties of microtubules and their functional significance for neurons (Tuszynski 2023)
- It’s very polarizable. It uses C-termini for ion fluxes going in and out of the lumen, which might have a helical conduction pathway. Badass
- Tubulin C-terminal tail regulation by intracellular pH
