Tribulus

2022-09-23:

Tribulus Terrestris (Gokshura) #

• The important compounds are the furostanol glycosides like:
  • Phytoandrogens
  • Protodioscin: A lot like pregnenolone/DHEA/Androstenediol. (The most important compound for the androgenic effects. ND and some other companies have extsacts)
    • Proerectile.
  • protogracillin.
  • Gitonin
  • Tribulosaponin A/B.
  • Harmine
    • Made Brendan.Henry intolerant to cold. This is because: Hypothermic effect of harmala alkaloid in rats: involvement of serotonergic mechanism
• https://men-elite.com/2019/06/18/tribulus-terrestris-not-so-useless/
  • Decreased prolactin, pro-DHT, and a potential DHEA mimetic.
• https://raypeatforum.com/community/threads/a-proposed-anabolic-mechanism-of-tribulus-terrestris-tt.26184/
• Evaluation of anti-depressant and anxiolytic activity of Rasayana Ghana Tablet (A compound Ayurvedic formulation) in albino mice
• Effect of Tribulus terrestris on nicotinamide adenine dinucleotide phosphate-diaphorase activity and androgen receptors in rat brain
  • Increases Androgen Receptor density
• Downregulates the HPA axis, inhibiting CRH/ACTH/cortisol release.
• Tribulus terrestris extracts alleviate muscle damage and promote anaerobic performance of trained male boxers and its mechanisms: Roles of androgen, IGF-1, and IGF binding protein-3
  • Lowers IGFBP-3
• Upregulates AR’s, decreases prolactin, increases DHEA, reduces IGFBP3 so more igf-1 is bioavailable, more conversion to free T/reduced SHBG, as total t is slightly reduced and free T slightly increased, is ACHEI, and reduces a few inflammatory cytokines. Prob missing some things… (edited). Makes you extremely horny.
• Raises liver enzymes. Idk if this necessarily implies a compromisation of function or anything though.
• Possible kidney complications: https://raypeatforum.com/community/threads/tribulus-increases-dht-levels.26612/post-536171
• Effect of tribulus terrestris saponins on behavior and neuroendocrine in chronic mild stress depression rats
• Effect of oral administration of Tribulus terrestris extract on semen quality and body fat index of infertile men
• Lowers blood sugar

Dose #

• NOW Sports is the best according to Uxkull. 1g.