yana-notes

Substance P

2022-04-07: reference:

Substance P(reparation? Pain?) #

An undeca-Neuropeptide.

  • JC: Somehow got permatolerance to capsaicin cream. Burned like hell first couple times, now even after not doing it for years it doesnt do jack. Is spinal substance P depletion permanent, or could some other mechanism be at play? Doesn’t happen orally, just topically and its non-local.