Osteocalcin

links: Hormones reference: 8-18-2021

Osteocalcin #

• AKA Bone gamma-carboxyglutamic acid-containing protein (BGLAP).
• Its synthesis is dependent on Vitamin K due to its GLA (Vitamin K-dependent carboxylation/gamma-carboxyglutamic) domains.
• Acts on Leydig cells to stimulate Testosterone biosynthesis.
• Essential part of the fight-or-flight response.
• Serum osteocalcin levels at 4 months of age were associated with neurodevelopment at 4 years of age in term-born children